Friday, May 10, 2013

And now, a possible cure for HIV, We hope.




hiv-virus_2548220bHere’s the post from The Telegraph that made us happy.
[Excerpts]
Five years ago, the general consensus was that HIV could not be cured. But then Timothy Ray Brown, an HIV sufferer — who has become known in the field as the Berlin Patient — developed leukemia.
He had a bone marrow transplant from a donor with a rare genetic mutation that made his cells resistant to HIV. As a result, in 2007 Mr Brown became the first man to ever be fully cured of the disease.
Replicating this procedure on a mass scale is impossible. Nevertheless, the Brown case caused a sea change in research, with scientists focusing on finding a cure as well as suppressing the symptoms.
Two principal approaches are currently being pursued. The first, gene therapy, aims to make a patient’s immune system resistant to HIV. This is complex and expensive, and not easily transferrable to diverse gene pools around the world. The second technique involves releasing the HIV virus from “reservoirs” it forms inside DNA, bringing it to the surface of the cells. Once it comes to the surface, the body’s natural immune system can kill the virus through being boosted by a “vaccine”.
The second approach is the one being pursued by Dr Søgaard and his colleagues in Denmark, the CHERUB group in Britain, and by other laboratories in the United States and Europe.
The technique is being researched in Britain, but studies have not yet moved on to the clinical trial stage. Five universities — Oxford, Cambridge, Imperial College, London, University College, London and King’s College, London — have jointly formed the Collaborative HIV Eradication of Reservoirs UK Biomedical Research Centre group (CHERUB), which is dedicated to finding an HIV cure.
The scientists are currently conducting human trials on their treatment, in the hope of proving that it is effective. It has already been found to work in laboratory tests.
We’re pretty excited about this. Imagine, we could be on the brink of having an HIV free generation. An HIV free World!

Meanwhile, let’s all stay hopeful. And remember we may not be the ones to save the world in one fell swoop, but we can save a person’s life now. By being kind, and being there, and lending a hand when needed.
[To Read the full post by Jake Wallis Simons, published on the Telegraph.co.uk.Click Here]

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